Cancer Testicular Cancer Testicular Cancer Guide Testicular Cancer Guide Overview Symptoms Causes Self-Check Treatment Facts Symptoms of Testicular Cancer By Lisa Fayed Updated on September 11, 2021 Medically reviewed by Douglas A. Nelson, MD Print Table of Contents View All Table of Contents Frequent Symptoms Rare Symptoms Later-Stage Symptoms When to See a Healthcare Provider Frequently Asked Questions Next in Testicular Cancer Guide Causes of Testicular Cancer Testicular cancer is a relatively uncommon cancer but one that can cause extreme distress to the roughly 9,600 American men estimated to be diagnosed in 2020. As there are no screening tests available to detect the disease, detection depends largely on your ability to spot its common (and not-so-common) symptoms, which may include a lump in the testicle, a heaviness in the scrotum, testicular pain, fatigue, lower back pain, and unexplained weight loss. By knowing the signs and symptoms of testicular cancer, you can be diagnosed and treated early and, more often than not, achieve complete remission. Illustration by Joshua Seong, Verywell Frequent Symptoms The most common sign of testicular cancer (also known as malignant neoplasm of the testes) is a lump in one and sometimes both testicles. The lump is usually found while taking a shower, when performing a routine testicular self-exam (TSE), or by your partner during sex. Testicular lumps are most often painless, although some do cause pain. They can also be movable or immovable. Some tumors may be smaller than a pea, while others can be larger than a marble. Many of the tumors will feel hard and rock-like. Other common signs and symptoms include: A feeling of heaviness in the scrotumA dull ache or sharp pain in the scrotum or lower abdomenThe swelling of one testicle but not the otherThe accumulation of fluid in a testicle While a testicular lump can be scary, it doesn’t necessarily mean that you have cancer. There can be many different explanations for this of which cancer may be the least likely. With that being said, you should never ignore a testicular lump or any other symptoms suggestive of cancer. Some men with testicular cancer may have no symptoms and will only be diagnosed during an unrelated medical exam (such as a fertility test or routine physical). Rare Symptoms There is a rare type called testicular choriocarcinoma that is extremely aggressive and is more likely to spread to the lungs, bones, and brain. Other uncommon forms, like embryonal carcinoma, are also more prone to metastasis. Testicular cancers like these can trigger the excessive production of a hormone known as human chorionic gonadotropin (HCG), also known as the "pregnancy hormone." If this occurs, a man may experience gynecomastia, the abnormal enlargement of breast tissue. Other types can cause gynecomastia by increasing the production of the female hormone, estrogen. One such example is Leydig cell tumors of which 10% will develop into testicular cancer. While testicular cancer is exceedingly rare before the age of 14, it can occasionally occur. If it does, early puberty (also known as precocious puberty) may be the first sign. The condition is most often associated with the development of Leydig cell tumors. Later-Stage Symptoms If left undiagnosed and untreated, testicular cancer may begin to spread, moving from the site of the original tumor (known as stage 1 cancer) to nearby lymph nodes (stage 2) and, finally, to distant organ systems (stage 3). The original cancer is referred to as the primary tumor, while the site of the new cancer is known as either a secondary or metastatic tumor. If metastasis does occur, the symptoms can vary based on the location of the secondary tumor. Among the possible signs and symptoms: Lower back pain may develop if the cancer starts to spread to nearby lymph nodes. Swollen lymph nodes may develop in the neck as the cancer further spreads to distant organs. Swelling and pain of the lower extremities may be a sign of a blood clot known as deep vein thrombosis (DVT). As cancer progresses, it causes a hypercoagulable state that creates a much higher risk of blood clots forming. Shortness of breath (dyspnea), a chronic cough, or the coughing up blood (hemoptysis) can occur if the malignancy spreads to the lungs. This is typically associated with a pulmonary embolism, in which a blood clot travels to the lungs from another part of the body, most often the legs. Headaches, confusion, and other neurological symptoms may develop if a secondary tumor is established in the brain. Chronic fatigue and unexplained weight loss are common signs of late-stage cancer. When to See a Healthcare Provider If you discover a lump on your testicle, see your healthcare provider as soon as you can. While it is important to be proactive and vigilant, try not to jump to conclusions or let anxiety get the best of you. Testicular Cancer Doctor Discussion Guide Get our printable guide for your next healthcare provider's appointment to help you ask the right questions. Download PDF Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life. Email Address Sign Up You're in! Thank you, {{form.email}}, for signing up. There was an error. Please try again. According to the National Cancer Institute, only around six of every 100,000 American men are diagnosed with testicular cancer each year, making it one of the least common causes of cancer in the United States. Unless you are at high risk, the chances are pretty good you’ll be cancer-free. Some of the more likely causes of testicular lump are infection and injury, either of the testicle itself or the tube through which sperm is transported from the testicle (called the epididymis). On the off-chance you do have cancer, treatment is such that more than 95% of cases have a five-year survival rate , including 73% of men diagnosed with metastatic disease. Frequently Asked Questions How quickly does testicular cancer spread? Of the two types of testicular cancer, seminomas spread faster than nonseminomas, but nonseminomas are more common. However, how quickly either type of testicular cancer spreads will vary depending on the patient. The American Urology Association warns that men wait five months, on average, to tell their healthcare provider about testicular cancer symptoms, and the cancer could spread in that time. Are there risk factors that make you more likely to develop testicular cancer? Several risk factors may make a man more likely to develop testicular cancer. These include a history of undescended testicle, family history of testicular cancer, previous testicular cancer, and HIV. Testicular cancer occurs most frequently in males aged 20 to 34, though it can occur at any age, and it's four to five times more likely to affect White males than Black or Asian-American males. Causes of Testicular Cancer 8 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. American Cancer Society. Key Statistics for Testicular Cancer. American Cancer Society. Signs and Symptoms of Testicular Cancer. Gheorghisan-galateanu AA. Leydig cell tumors of the testis: a case report. BMC Res Notes. 2014;7:656. doi:10.1186/1756-0500-7-656 American Society of Clinical Oncology. Testicular Cancer: Symptoms and Signs. National Cancer Institute. Cancer Stat Facts: Testicular Cancer. National Cancer Institute. Cancer Stat Facts: Testicular Cancer. Urology Care Foundation. What is testicular cancer? American Cancer Society. Risk factors for testicular cancer. Additional Reading National Cancer Institute. Cancer Stat Facts: Testicular Cancer. Bethesda, Maryland. Hanna, N. and Einhorn, L. Testicular Cancer. N Engl J Med. 2014; 371:2005-16. DOI: 10.1056/NEJMra1407550. Julián, M.; Pizarro, E.; Martínez Peralta, S. et al. Gynecomastia as Unusual Presentation of Primary Choriocarcinoma of the Colon: A Case Report and Literature Review. AACE Clin Case Rep. 2015; 1(4): e260-e264. DOI: 10.4158/EP14485.CR. Mendez-Gallart, R.; Bautista, A.; Estevez, E. et al. Leydig Cell Testicular Tumour Presenting as Isosexual Precocious Pseudopuberty in a 5 Year-old Boy with No Palpable Testicular Mass. Clin Pediatr Endocrinol. 2010; 19(1):19-23. DOI: 10.1297/cpe.19.19. By Lisa Fayed Lisa Fayed is a freelance medical writer, cancer educator and patient advocate. See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit